This means that fipronil-sulfone is many times more toxic to mammals than fipronil itself. Read More: Bravecto® Review (Warning) | The Truth About Bravecto. Lethargy – Owners who have reported deaths of their cats and dogs often report signs of lethargy in their animal. FRONTLINE Gold packs 3 powerful weapons: pyriproxyfen and S-methoprene, which kills reinfesting flea larvae and eggs before they have a chance to develop into adults, and fipronil, which eradicates adult ticks and fleas. You’ll want to talk with your vet if the side effects persist longer. Everything You Need to Know, Bravecto® Review (Warning) | The Truth About Bravecto, disclaimer on the rate table(s) displayed. Tick-borne illnesses are Lyme Disease, Ehrlichia, anaplasmosis, Rocky Mountain spotted fever or babesiosis. Frontline Gold is available in 3, 6, and 12 pack doses. The reviewers commented that further research might find fipronil is absorbed at higher levels through damaged or unhealthy skin. While Frontline comes in topical dosages specifically for cats and different sizes of dogs, there's also a spray version. Click here to read AdvisoryHQ’s disclaimer on the rate table(s) displayed on this page. These studies only look at immediately visible symptoms and fail to account for long-term effects that are often harder to see. Product details The New Zealand and United Kingdom websites do address safety concerns on their Q&A pages. 4. Popular Article: Frontline Plus Reviews – Is It Really Safe? See Also: Bravecto® for Cats (Reviews) | Is it Safe? [Related] Are oral flea and tick meds any better? The effects range from mild to severe, depending on the amount of exposure and condition of your cat. Frontline is available in four dosages: For dogs above 132 pounds, it is best to speak with your vet to ensure that the correct—and safe—dosage is applied. The net effect is over-excitation of the CNS, which causes the death of the insect. Depending on whether you need Frontline Plus for Dogs 5-22 lbs., 23-44 lbs., 45-88 lbs., or 89-132 lbs., there will be slight differences in price for each retailer. What You Need to Know. Frontline Plus also contains S-methoprene, a compound that has been in use since 1977 that stops juvenile insects from turning into adults. Always read the label and follow the directions carefully. Frontline Plus is used monthly on dogs and cats. In the process, we’ll also answer the following questions to help you determine whether Frontline for Dogs is the best flea and tick treatment for your four-legged family member: Frontline for Dogs Reviews | What is Frontline for Dogs? For example, in their 2014 report, Tad Coles and Michael Dryden conclude that a suspected lack of efficacy by pesticides and acaricides is not caused by resistance within the pest population, but likely due to: In his 2016 report, Michael K. Rust conducted and examined research on whether fleas were still susceptible to fipronil and other pesticides. It also blocks a receptor, GABA, which has a similar form in mammals, and a receptor called GluCl, which doesn’t exist in humans. Frontline Plus is produced and owned by Merial, the animal subsidiary of Sanofi, a multinational pharmaceutical company. Needless to say, we’re not wasting any more money buying something that just doesn’t work for us, and are experimenting with other products. The bigger issues is, these treatments often do more harm than good. Once the binder has accomplished its task, the threat is dispelled from the digestive tract. Two of the ingredients in this formula, pyriproxyfen and (S)-methoprene, are chemical "growth regulators". Monitor your cat after application. Apply geranium oil to the collar of your dog to prevent fleas and ticks. October 4, 2014 … Fleas are a pain (literally) – a nightmare that all dog owners face at some point. Frontline Side Effects There are many concerns about possible side effects, the most common being skin reactions like hair loss, itching, and redness, and neurological issues like uncoordinated movement and lethargy. Frontline Plus has two potent ingredients that work effectively to kill and prevent flea infestations. Frontline for Dogs Reviews | What Types of Frontline for Dogs Products Are Available? © 2021 Dogs Naturally Magazine Inc. Frontline Side Effects Since the active ingredient fipronil works as a pesticide, it's important to avoid using the treatment along with other pesticides. With Frontline Gold for Dogs, your dog may experience the usual topical solution reactions, such as skin irritation or other signs of discomfort. A review of Frontline Plus side effects and the safety literature on fipronil was done on behalf of the Australian Pesticides and Veterinary Medicines Authority (APVMA). Frontline for Cats Reviews | Frontline for Cats Side Effects. With regard to allergic reactions, “most of these reactions are mild and don’t require treatment” she added. This is an easily avoided error, simply double check your order before purchase. Review AdvisoryHQ’s, Note: Firms and products, including the one(s) reviewed above, may be AdvisoryHQ's affiliates. If these or other side effects occur, consult your veterinarian or call 1-800-660-1842, M-F 8am-8pm EST. What You Need to Know, Bravecto® For Dogs (Reviews) | Is it Safe? The Difference Between Frontline Plus And Gold. Contains: fipronil and (S)-Methoprene and pyriproxyfen make it relentless at killing fleas, flea eggs and larvae, as well as ticks. Applied between the shoulder blades as a topical solution, Frontline Spot on Top for Dogs provides full protection for 30 days. Note: Because Frontline Plus is the most popular version, the sections below will focus on Frontline Plus for Dogs reviews, rather than the Gold or Spray topical treatments. If irritation lasts for several days you should consult your veterinarian. Finally, it emphasizes the importance of following the label on the products, especially in using the correct drug for cats or dogs, and to use the correct dosage. According to the product website, the Frontline Plus for Dogs line of flea and tick medication is safe for puppies that are at least 8 weeks of age. If these or other side effects occur, consult your veterinarian or call 1-800-660-1842, M-F 8am-8pm EST. Only use Frontline as recommended, which is once a month. This review of Frontline Spray, Frontline Gold, and Frontline Plus for dogs includes a detailed overview of Frontline flea and tick products for dogs, the ingredients contained, and how they might affect your dog, and the side effects that might be experienced (large dogs, small dogs and puppies experience different side effects, which you need to watch out for). Conclusion FRONTLINE ® CUSTOMER SERVICE. Before administering Frontline Spray, Frontline Gold, or Frontline Plus, every cat owner should be aware of the possible side effects. It’s always good to be prepared and knowledgeable of all possibilities in order to minimize and prevent unnecessary negative reactions. The highest number of Frontline Plus for Dogs reviews can be found on 1-800-PetMeds, with nearly 4,100 comments on the Frontline flea treatment for dogs. If you’re on the fence about whether Frontline for Dogs is the best choice for your pet, you may want to consider what other pet owners have said about the product. Dr Christina Chambreau is another vet from Maryland who has seen similar cases and has a similar attitude towards the product. Frontline Plus is one of the top flea and tick medications because it’s effective, easy-to-use and non-intrusive; however, a small minority of & Frontline users has reported side effects in their pets. Monitor your dog after application. While some dog owners reported trying Frontline for the first time and not seeing results, many critical Frontline Plus for Dogs reviews came from pet parents that had used the topical solution for years, only to find that it seemed to suddenly stop working. Our Maine Coon Andy, Annie's brother survived although he had minor side effects. Merial also produces Heartgard to prevent heartworm, NexGard, a chewable flea and tick poison that was released in 2013, and a series of vaccines for cats. Frontline Plus should not even be sold! Dangers of Frontline - Frontline Poisoning - Frontline Dog Side Effects. It is intended for use on kittens and puppies over 8 weeks of age and can be used on pregnant or lactating animals. Once FRONTLINE Gold is applied, fipronil stores itself in the oil glands in your pet's skin. Frontline Gold cause my dog to have seizures and tremors! Sevalamer (Renagel) is a polyamine that has been shown to bind phosphates without raising calcium levels. Don’t Miss: Bravecto® For Dogs (Reviews) | Is it Safe? Interestingly, finding information on the side effects for Frontline Plus and the rest of the brand is somewhat difficult, as the company does not appear to publicly list side effects. He too grieved for months after her passing. The article states “Individual variation in response to fipronil is to be expected.” It warns that adverse reactions should be a sign to stop using it. Critical Frontline Plus for Dogs reviews from 1-800-PetMeds echo much of the same sentiment, with many dog owners complaining that, although the product used to work in the past, it become ineffective. This increased toxicity to mammals includes humans – so your child can absorb the chemical when she cuddles with your dog who’s been treated with Frontline. Our Maine Coon Andy, Annie's brother survived although he had minor side effects. To actively repel fleas, she recommends products like neem oil. Skin issues — As mentioned earlier, fipronil can cause irritation to your dog’s skin. What are the side effects of Frontline Gold for Cats and Kittens? SIDE EFFECTS. Frontline for Dogs Reviews | Where Can I Buy Frontline for Dogs? Your pet will not experience any severe side effects if it is healthy, is not allergic to any of the main ingredients, and is given the correct dosage of Frontline Plus monthly. Pets may experience redness or irritation at the site of application. Flea and tick medicine poisoning occurs when your cat has a negative reaction to the medication. Frontline Gold for Dogs provides the same flea and tick protection of Frontline Plus, but with one extra ingredient: pyriproxyfen, which boosts the medication’s ability to kill eggs, larvae, and chewing lice. Although the Frontline Spray for Dogs is available at Petco, Amazon, and 1-800-PetMeds, there does not seem to be a US-based website for the product. Additionally, Frontline Gold for Dogs is safe for animals that are breeding, pregnant, or lactating, making it easy for pet owners to administer treatment at any time. Frontline’s weight distinctions are: five to 22 pounds, 23 to 44 pounds, 45 to 88 pounds, and 89 to 132 pounds. Also minimize the use of unnecessary pharmaceuticals. The symptoms go away within a month. It’s been an ongoing battle since Spring, regularly treating the dogs and the inside/outside home environments trying to prevent further infestations. I have used this product for many years and it works great for me. In the bodies of dogs and other mammals, fipronil primarily converts into fipronil-sulfone. I applied Frontline Plus for the first time on my 15 month old dog. Flea and tick pills made using isoxazoline can cause neurological problems in cats and dogs, the FDA says, and labels need to warn of the risks more clearly. I am devestated. I have used front line before and it worked great. Of course, as every dog parent knows, dogs can quickly become much more than a pet, fitting in as an integral part of the family. She has strong concerns over its toxicity to the pet and she has confidence in the efficacy of alternative methods. However, the studies on fipronil’s rate of passage through the skin only look at animals with healthy skin. Moreover, Frontline Gold may have adverse side effects on pregnant and lactating dogs hence it is important to seek the advice of a veterinarian before using the product on your pets. Frontline Plus Ingredients. On examining the cat, she found him to be very lethargic and when he started to walk, he had a very uncoordinated gait. It's in the top 3 bestselling flea drops and has quite a few popular alternatives in the same price range, such as Merial Frontline Plus for Dogs or Vectra Green For Large Cats. Frontline Gold is available in 3, 6, and 12 pack doses. No apparent side effects on pets (Care should be taken to dose the pet properly) But recently, we have been receiving feedback from our customers about the ineffectiveness of this product on their pets. According to various consumer sites, potential side effects of Frontline for Cats include: Temporary redness or … If you have a rabbit or other pet, note that Frontline is highly toxic to rabbits and Frontline is labeled “Do Not Use On Rabbits. Side Effects. If you are still seeing fleas and ticks, rest assured that the medication is working, and the pests will die off. Please support the hard working holistic vets who make this information possible. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. This review of Frontline Spray, Frontline Gold, and Frontline Plus for dogs includes a detailed overview of Frontline flea and tick products for dogs, the ingredients contained, and how they might affect your dog, and the side effects that might be experienced (large dogs, small dogs and puppies experience different side effects, which you need to watch out for). With Frontline Gold for Dogs, your dog may experience the usual topical solution reactions, such as skin irritation or other signs of discomfort. The report on Frontline Plus for Dogs shows that of a total of 2469 incidents, they classified: The EPA found that most of the reactions involved systemic, application site, digestive, neurological and behavioral disorders. Frontline for Dogs was created by Merial, now a part of, Frontline Spray for Dogs is safe to use on puppies that are at least 8 weeks of age. My dog has been throwing up and seems to be extra sleepy/lazy, the last two weeks. Altogether, Sanofi reported a net profit on these products of $706 million in 2015. Because Frontline Plus for Dogs is stored in your pet’s oil glands, any fleas, ticks, and chewing lice will die within hours of coming into contact with their haircoat, even before they have the chance to bite. Of course, there are always side effects as well and with Frontline, these include itching, swelling, and irritation. Side Effects of Frontline Plus for Dogs Frontline Plus for dogs is topical medication that works against tick and flea infestations. No matter what size, breed, or age, you want to make sure that your four-legged family member is happy, healthy, and safe—which means regular vet visits and preventative flea and tick treatment. Despite being widely available from online and physical retailers, dog owners would be much better off visiting their veterinarian to ensure that Frontline is both stored and applied properly to get the best results. I also foster dogs for a rescue and use this on them as well, with great success. If your cat manages to ingest the medication, the side effects are usually mild. Seizures occur as the sensitive pet may capture the neurotoxicity of Fipronil. With high ratings, the vast majority of these reviews are positive. This means a healthy diet and physical activity. Reasonable efforts have been made by AdvisoryHQ to present accurate information, however all info is presented without warranty. The skin can become red and irritated, causing itching and promoting your dog to lick or scratch at the site. Skin irritation: The skin sensitizing effect of Fipronil causes skin irritation, redness, soreness, dermatitis and swelling of skin. To date, the Frontline® brand is one of the top two selling flea and tick products, with billions of doses administered since the 1970s. Always make sure you are giving Kitty the correct dosage. The Best Dog Food For German Shepards. The two active ingredients include: ... Frontline is a topical antiparasitic drug that aims to destroy ticks and fleas in various forms, including flea larvae and eggs. Of course, there are always side effects as well and with Frontline, these include itching, swelling, and irritation. Conclusion: Is Frontline for Dogs the Best Flea & Tick Medication to Use on Your Pet? If you have any reservations about using pesticide-based flea and tick treatments for your dog, there are plenty of natural alternatives to consider, which may be a good option for pet owners that still have doubts over the safety and efficacy of Frontline Plus for Dogs. Flea and tick pills made using isoxazoline can cause neurological problems in cats and dogs, the FDA says, and labels need to warn of the risks more clearly. Research by the EPA in 2009 examined incident data for spot-on pesticides used on dogs, including fipronil products for dogs and cats. Dog Deaths & the Truth About Bravecto®. “Frontline Plus has a long established and wide margin of safety and your cat should be fine,” was the response from the New Zealand website to an owner who was concerned about whether her pet would see problems from her inadvertent over-application of Frontline. On the "Las Vegas Nurses Strong" Facebook page, responses varied from either no side effects. Fipronil inhibits the insect GABA receptor much more effectively than the human receptor, making it more toxic to insects than mammals. As it is the case with any other medicine, there have been reported side effects when using both Frontline products, so precaution is always recommended. But since moving to TX six months ago, Frontline completely failed working against fleas and all three dogs became heavily infested, much to our horror. I always bathe them in blue Dawn first to rid them of any fleas, then apply this product. Frontline, a common flea preventative that disrupts flea neural receptors, is a suspected carcinogen and endocrine disruptor that can be toxic to the nervous system if ingested. Although this sensation should subside, persistent irritation warrants a vet check. Want to know how you can keep the fleas and ticks away naturally? Most Common Side Effects of Frontline for Dogs. Could fleas and ticks be developing an immunity to Frontline for Dogs? Yes, I want to get emails from Dogs Naturally. I live in Texas and it works great. The dog dies from liver cancer two years later. In some cases, Frontline Gold can be used as Frontline for Puppies, as it is suitable for use on puppies that are at least 8 weeks old and weigh at least 5 pounds. Based on Frontline Plus for Dogs reviews from pet parents, there seems to be a great deal of debate over whether Frontline will continue to work for your dog over the long-term. Dr Lichtenberg warns that by choosing to use more natural protection against ticks or fleas, your dog will get more ticks and be at a greater risk for developing tick-borne illness. When asked about side effects, the UK website’s response was, “side effects could occur but these tend to be mild and temporary in the majority of cases.”. Some pets have diarrhea, loss of appetite or even excessive salivation; however, side effects generally disappear within 24 hours or less. The primary active ingredient in Frontline for Dogs is fipronil, a broad-spectrum insecticide that attacks the central nervous system, effectively killing adult fleas and ticks. We applied Frontline Gold for the first time ever to our dog on 01/16/20. Ramelmeier stopped using it after seeing a connection between its use and cases like this. In his free time, he enjoys backpacking, yoga, journaling, and playing soccer. AdvisoryHQ (All Rights Reserved), One of the most popular—and longest-running—flea and tick treatments is. Note: Firms and products, including the one(s) reviewed above, may be AdvisoryHQ's affiliates. If you’d like more on how we use your information, just check out our Privacy Policy. Frontline Gold is an over-the-counter topical. However, these side effects are not addressed anywhere on the US website for Frontline. Click to view AdvisoryHQ's advertiser disclosures. They found him under a bench “looking like a puddle,” Dr Chambreau said. Moreover, Frontline Gold may have adverse side effects on pregnant and lactating dogs hence it is important to seek the advice of a veterinarian before using the product on your pets. Common threads among all positive Frontline Plus for Dogs reviews include: While there are plenty of positive Frontline for Dogs reviews, there is also a significant number of dissatisfied pet parents that would not recommend Frontline flea treatment for dogs. This product has worked very well for us and have not had any adverse reactions from any of the dogs.”, Similarly, user Maggiesmom says that “Frontline has always been my go to for ticks and fleas prevention for my dogs and cats! There were also symptoms reported from exposure to fipronil by humans, including nausea, vomiting and headache. Lee Carter is a University of Delaware honors biology major who hopes to attend medical school after he graduates. Click to view AdvisoryHQ's, ► Get Featured on AdvisoryHQ. Gastrointestinal signs such as vomiting or diarrhea have also been reported. I live in the woods with a lot of ticks, and I get great result[s].”. Origins: On 27 May 2015 a Facebook user published the message and photograph shown above about Frontline Plus (a popular flea and tick remedy for pets known generically as Fipronil) and an adverse reaction Frontline Plus and Gold are available in a number of size ranges, and if you buy a dose appropriate for a large dog when your pup is only medium, it could result in uncomfortable side effects. Waited 3 weeks and used it again and it didn’t seem like it helped at all. The two active ingredients include: Frontline for Cats (Reviews) | Is It Really Safe for Cats and Kittens? The applicator is also longer and thinner to allow for easier application of Frontline flea and tick for dogs. Any side effects must be reported to your veterinarian. Thanks. To find a holistic or homeopathic vet near you or to find one who will do phone consultations, visit The Academy Of Veterinary Homeopathy. The irritation should go away within a couple of days, but if it becomes worse within a few days, then go see your veterinarian. In addition to the retailers listed above, you may also be able to buy Frontline for Dogs and Frontline Plus for Dogs from your veterinarian, which is the recommended method. I have been using frontline plus for cats for a couple years and the last treatment I gave my 4 cats killed 2 of them. It’s always good to be prepared and knowledgeable of all possibilities in order to minimize and prevent unnecessary negative reactions. Lots of people turn to chemical spot on treatments to combat the problems. Unfortunately, with almost otherworldly contortion abilities, she may reach it anyway. Dr Chambreau, Dr Jennifer Ramelmeier and many other holistic veterinarians are critical of studies like the ones in the APVMA review. Frontline Gold is an over-the-counter topical. Frontline Gold for Dogs and Puppies is a potent monthly topical spot-on treatment that kills fleas, flea eggs, flea larvae, ticks and chewing lice.It's three active ingredients fipronil, (S)-methoprene and newly added powerful third ingredient pyriproxyfen helps to kill the next generation of flea eggs and larvae before they can develop into adult fleas. The waterproof medication works to terminate insect life … Monitor your cat after application. Fipronil acts by disrupting the central nervous system (CNS), which contains the brain and the spinal cord. If these or other side effects occur, consult your veterinarian or call 1-800-660-1842, M-F 8am-8pm EST. Frontline Gold for Cats is a well-known option at the top of the price range. While the product does appear to be safe, it’s worth mentioning that there will always be risks associated with any flea and tick medication, as they all use at least one form of pesticide. She told the story of a friend’s cat who had received Frontline Plus two or three hours earlier and went missing while she was visiting. She’s found that after she treats an animal for any type of problem, particularly behavioral or neurological, if the owners apply Frontline or other similar pesticide products, the symptoms that she’s treated come back.